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Evaluation of growth hormone (GH) action in mice: discovery of GH receptor antagonists and clinical indications

This dual approach delivers the peptide both systemically and directly to follicles, addressing hair loss from multiple directions simultaneously

In some histological and electrophysiological experiments, AgRP-IRES-Cre or LepR-IRES-Cre mice were also crossed with the Cre-inducible tdTomato-reporter mouse (B6;129S6-Gt(ROSA)26Sor tm9(CAG-tdTomato)Hze /J, The Jackson Laboratory), allowing the visualization of AgRP or LepR neurons via expression of the tdTomato fluorescent protein