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Sublingual forms appear similarly effective to standard oral tablets

Key search concepts included *Ganoderma lucidum* polysaccharides, diabetes mellitus, inflammatory responses, programmed cell death (apoptosis), insulin resistance and sensitivity, oxidative damage, pancreatic islet function, glycolipid homeostasis, gut microbiota modulation, multimodal or integrative therapies, structural or formulation advancements, diabetic nephropathy, hepatotoxicity, cardiovascular complications, chronic non-healing diabetic ulcers, neurodegenerative and neuropathic manifestations, and diabetic retinopathy

pCR, pathological complete response

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