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This distinction matters because allergic itching would warrant immediate discontinuation, whereas GLP-1-related itching often resolves with continued use or temporary dose adjustment

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[Google Scholar] Saruhan N, Terzi R, Saglam A, Kadioglu A

Other pharmacological options, such as orlistat, phentermine, and the phentermine-topiramate combination, are approved for pediatric use but generally yield less weight reduction than GLP-1R agonists