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Clear dose-response relationships : Longer acetaminophen use correlates with higher attention/focus disorder risk, with strongest evidence linking prenatal NAPQI exposure to attention and behavioral disorders

To an extent, yes

J Clin Investig 107:135142 Yang Y, Liu Z, Chen J, Wang X, Jiao Z, Wang Z (2024) Factors influencing methotrexate pharmacokinetics highlight the need for individualized dose adjustment: a systematic review

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