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In cases where a patient presents with recurrent kidney infections or other underlying health issues, a referral to a urologist or nephrologist may be recommended for comprehensive evaluation and treatment

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For example, brain derived neurotrophic factor (BDNF) and TNF protect neurons against excitotoxicity through activation of the transcription factor NF-kB, which induces the expression of antioxidant enzymes such as Mn-SOD and the anti-apoptotic proteins, Bcl-2 and inhibitor of apoptosis proteins IAPs [123,124]