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Cagrilintide monotherapy produces less gastrointestinal distress than retatrutide, making it a better option for researchers who are sensitive to nausea, constipation, or diarrhea
While GLP-1 and GIP respond to sustained moderate levels, glucagon receptor activation appears more threshold-dependent
Before a potential new therapy can be publicly marketed, it must go through the four phases of clinical trials, with a preclinical phase initially (also referred to as phase 0)
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