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In the previous pilot clinical trial, an effect on survival was observed using a dosage of 3 g/day, while in our observational study, the effective dose was 1.5 g/day and, unexpectedly, no effect was observed in subjects treated with 3 g/day

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Suppression of TGF-mediated conversion of endothelial cells and fibroblasts into cancer associated (myo)fibroblasts via HDAC inhibition