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This effect is partially lost in GF mice, suggesting a microbiota-dependent mechanism

5.2.4 Ferroptosis suppressor protein 1 and coenzyme Q10 pathway FSP1 possesses NAD(P)H oxidoreductase activity and reduces CoQ to ubiquinol (CoQH2), which inhibits lipid peroxidation and ferroptosis by trapping lipid peroxidation free radicals (77, 78)