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The primary mechanism of action has been speculated to involve their ability to increase the viscosity of contents of the upper GI tract and, hence, slow gastric emptying [23]

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For many Americans who want to lose weight, the desire to start a GLP-1 drug in 2026 exists in theory, but remains contingent on whether the economic barriers to access can be overcome

Butsch, who has previously consulted for Novo Nordisk (maker of Wegovy) and Eli Lilly (maker of Zepbound), said he was already concerned about the ubiquity of compounded semaglutide and tirzepatide in recent years