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Interestingly, one of the mechanisms that causes POTS is a disturbance in the renin-angiotensin system, possibly due to inadequate ACE2 activity, which is one of the receptors used by the SARS-CoV-2 virus in causing Covid.[ref][ref][ref] POTS is a common autonomic disorder following Covid and in long Covid.[ref][ref] Some researchers point to SARS-CoV-2 invading the central nervous system in POTS, while others point to the changes in endothelial function

Last updated May 2011 (EMA) 10

PubMed Klicek R, Sever M, Radic B, et al