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Retatrutide must get approval from the regulatory agencies before people can use it

Retatrutide has not received MHRA marketing authorisation and is not currently available on the NHS or via private prescription in the UK

The 12mg-cohort escalation consumes 2 + 2 + 2 + 2 + 4 + 4 + 4 + 4 + 8 + 8 + 8 + 8 + 10 + 10 + 10 + 10 = 96 mg over 16 weeks before reaching peak maintenance dose, meaning two 30mg vials cover the full escalation period, and subsequent maintenance can be planned around a 30mg-vial cadence (2.5 weeks of supply per vial at 12mg/week)

Many patients begin to notice a reduction in appetite within the first week of starting semaglutide