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In this study, DIO mice were either allowed to feed ad libitum or were calorically restricted to induce 20% body weight loss prior to 12-week treatment with either 2.64, 10.8, or 53.4 nmol of AZD2820 per day via SC minipump infusion

also known as Compound 2) is a unique small-molecule agonist based on quinoxaline and allosteric modulator of GLP-1Rs with the potential to add the affinity for its receptor, first discovered by Knudsen et al

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