glp-1/gcgr dual agonist Discovery of Biased Dual-Agonists of Glucagon-Like Peptide 1 and Glucagon Receptors through Mutation of a Conserved Aspartate Dual GLP-1/GIP receptor agonists mechanism

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We assessed the diverse functional association of protein domains by analysing core functional clans, and determined similar patterns of dominance for carbohydrate, amino acid and lipid processing-associated domains (Extended Fig

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