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Parasutterella relative abundance was significantly higher in both the vehicle- and 5A-1MQ-treated groups switched from WD to LD relative to the LD and WD control groups (Fig

This may be related to the reduction of butyric acid-producing members of clostridial cluster, such as Clostridium coccoides and Clostridium leptum , and the abundance of Fecalibacterium prausnitzii and Roseburia intestinalis was significantly associated with severe of UC [149, 150]

When there is an excess of propionic acid, it can alter metabolic and immune pathways, gene expression, and synaptic plasticity as seen in autism

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