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Another case series enrolled 30 Chinese women with melasma, who took 25 mg pycnogenol three times daily for 30 days, leading to a 32% mean area reduction and a 22% intensity reduction of facial melasma [86]

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hCiPSC-NSCs treatment effectively reversed these pathological changes, enhancing antioxidant defenses while reducing oxidative damage, thereby restoring redox homeostasis in the prefrontal cortex

Certain health conditions such as intestinal or stomach problems, poor nutrition, cancer, HIV, pregnancy, old age, veganism and alcoholism can cause vitamin B12 deficiency