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GLP-1 exerts several key physiologic effects: Increases glucose-dependent insulin secretion Suppresses inappropriate glucagon release Delays gastric emptying Promotes satiety and reduces appetite Pharmacologic GLP-1 receptor agonists, including semaglutide, liraglutide, and tirzepatide, are engineered to resist DPP-4 degradation, allowing them to persist for hours to days

After your surgery heals, these insights help ensure smooth resumption of your compounded semaglutide at the right dose for your metabolism

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Liraglutide (Saxenda) earned FDA approval in 2014 to treat weight loss, but GLP-1s as a class took off with the 2021 approval of semaglutide (Wegovy) for chronic weight management