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Patients should follow the instructions provided by their clinician and dispensing pharmacy for preparation, dosing, and injection technique

These key factors can slow progress: metabolismhow fast your body burns calories at rest whether you dose as directed or skip doses lack of consistent lifestyle changes like diet and exercise stopping because of side effects age having a lower starting weight, BMI, or waist circumference The Bottom Line Both liraglutide and semaglutide help control blood sugar, support weight loss, and lower cardiovascular risk

Among Americans who have never taken GLP-1s but are considering beginning treatment in the next 12 months, 25.1% cite the pill option as the primary factor influencing their desire to begin treatment, and among the 9.3% of Americans who have discontinued GLP-1 treatments, 44.1% say they are considering resuming treatments because of pill options

Compounded semaglutide and tirzepatide maintain efficacy over 12+ months with well-characterized safety profiles