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The practical implication: IGF-1 LR3 cycles should not exceed six weeks, followed by an equal or longer washout period to allow receptor re-sensitization

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Similarly, Rezaie holds GLP-1s prior to elective endoscopic procedures, including colorectal cancer screening, since their use may affect gastric motility and colonoscopy prep

The latter refers to the structural and functional changes in the heart in response to cardiac injuries or chronic diseases, further exacerbating the negative impact on heart function