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And TRANSCEND-T2D-1, part of a separate three-trial diabetes-specific program, confirmed -2.0% HbA1c reduction and 16.8% weight loss in 537 type 2 diabetes patients (topline March 2026, published in The Lancet, June 2026)
Exendin-4 stimulation triggered a small increase in mitochondrial membrane potential under 6 mM glucose conditions, with this response further enhanced under increased (20 mM) glucose concentrations
Gao Q, Mei F, Shang Y, Hu K, Chen F, Zhao L, et al
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