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At this stage, transplantation is usually the main treatment option

Clinical studies have confirmed that hyperhomocysteinemia is not only an independent risk factor for the development of cardiovascular and cerebrovascular diseases, such as atherosclerosis, acute myocardial infarction, stroke, coronary artery lesions, and peripheral vascular disease, but also increases the risk of neurodegenerative disorders and tumors, and impairs the efficacy of antifolate drugs

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The other workers had occasional exposure to ethylene oxide, and 7 operators had relatively high exposure (amount unspecified) during the sterilization process