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Dosing Window The prescribing information specifies: take oral semaglutide with no more than 4 ounces of plain water, at least 30 minutes before the first food, beverage, or other oral medication of the day [21]

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Previously, we have shown that chemogenetic activation of GIPR-expressing cells in either the hypothalamus or the hindbrain supresses food intake 7,8 , and GIPR-expression in oligodendrocytes has recently been linked to enhanced access of co-administered GLP-1R agonists 23