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Figure 9 Neuroinflammation PET imaging has displayed elevated cytokines in the spinal cord and brain (46, 354), as well as increased activation of astrocytes (46, 354) and microglia (46, 47, 354)

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LD50 is a crucial number for determining the safety of any drug, and it is typically determined through animal testing, with known LD50 values for common substances like caffeine and aspirin 4m6s

Amidation involves conversion of the C-terminal carboxyl group (COO) to a neutral amide (CONH)