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These medications: Decrease hepatic triglyceride accumulation by reducing de novo lipogenesis 19 Lower the expression of SREBP-1c and SCD-1, key regulators in fat production 19 Increase PPAR- expression, enhancing the breakdown of fatty acids 19 Reduce inflammation and oxidative stress that drive liver damage 19 Studies show these liver benefits arent entirely dependent on weight loss

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This peptide, which they named 'exendin-4', not only stimulated insulin secretion in the same way as GLP-1 but also had the advantage that it remained active for more than two hours after subcutaneous injection