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Transcriptional analyses of intestinal epithelial cells indicated altered epithelial differentiation correlating with an inflammatory metabolic fingerprint

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We have therefore included a table of all our statistical analyses with effect sizes as a reference for power analyses for future studies

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A large population-based cohort study published in 2024 demonstrated that both diagnosed and self-reported constipation were prospectively associated with an elevated risk of depression, suggesting that constipation may be an independent risk factor or prodromal symptom of depression (Yun et al., 2024)

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