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Most side effects of liraglutide occur after its initiation or when the dose is rapidly increased

doi: 10.1039/D4FO00535J 134 LeeuwendaalN

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The ground-breaking finding that mice expressing dominant-negative N-cadherin, an adherent junction protein, develop spontaneous (not induced using chemicals or infections known to induce colitis in mice) inflammation in the gut epithelium further supports the key role of cell-to-cell adhesion, especially in its capacity to contribute to overall mucosal barrier function in regulating mucosal immune homeostasis