glutathione and methylation Glutathione: The “Master” Antioxidant – Core Med Science Understanding glutathione and the methylation

Eating sulfur-rich vegetables like broccoli and garlic can help provide the raw materials your body needs to build its own supply

doi: 10.1016/j.plaphy.2013.05.032 18 GriffithO

The National Institutes of Health recommend the following daily dosage of vitamin B12: Birth to 6 months: 0.4 micrograms Infants 712 months: 0.5 micrograms Children 13 years: 0.9 micrograms Children 48 years: 1.2 micrograms Children 913 years: 1.8 micrograms Teens 1418 years: 2.4 micrograms Adult men and women 1850 years: 2.4 micrograms Adult men and women over 50 years: 25250 micrograms Women who are pregnant: 2.6 micrograms Women who are breastfeeding: 2.8 micrograms Adults over the age of 50 are at a greater risk of vitamin B12 deficiency because they tend to produce less stomach acid, which is needed to convert the vitamin properly

SWI/SNF chromatin remodeler ARID1A-deficient cancer cells show vulnerability towards oxidative stress that arises from GSH depletion due to the reduced expression of the SLC7A11 cysteine transporter, which also regulates folate metabolism [41,189]