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Previous studies reported that the presence of curcuminoids is associated with anti-inflammatory capacity, which is attributed to a reduction in lipid peroxidation, inhibition of the binding of the transcription factor NF-B (nuclear factor kappa B) to DNA, leading to a decrease in pro-inflammatory cytokine concentrations, as well as a reduction in circulating inflammatory levels of gamma interferon and inhibition of COX-1 (cyclooxygenase-1 enzyme), COX-2 (cyclooxygenase-2 enzyme), and LOX activities (53, 58)

Regular follow-up labs at weeks 4, 8, 12, and 24 track A1C, fasting glucose, and kidney function to ensure safety and efficacy

They may offer several long-term solutions, such as prescription creams or cosmetic procedures, that may help reduce swelling, discoloration, and pigment issues under your eyes