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Whether GLP-1 receptor agonists might act on the dopamine cascade or suppress addictive impulses via other pathways has yet to be determined

BPC 157 has demonstrated anti-inflammatory effects, which can help reduce swelling, pain, and discomfort associated with injuries

Notably, GLP-1 RAs tend not to significantly affect diastolic pressure in most patients, likely because their vasodilatory effect primarily impacts systolic pressure and large artery compliance

Rates were 0.7% among those with alcohol use disorder and 1.6% for those with opioid use disorder presumably in those with comorbid diabetes/weight issues and substance use disorder