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In contrast to the excitatory effects of H1R and H2R, binding of the H3R by histamine results in a suppression of neuronal activity and inhibition of neurotransmitter release ( Central histaminergic system and the regulation of feeding Histamine synthesis The central histaminergic system has been implicated in the regulation of food intake through multiple different strategies used to manipulate the system

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Instead, you're supporting your body's own regulatory systems to function more optimally