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Curcumin, well documented for its potent anti-inflammatory activity also acts on Nrf2 and leads to improved total antioxidant capacity and an increase in endogenous anti-oxidant production, such as catalase, but only when retained as the free form
It is found in every cell of the body and plays a pivotal role in detoxification, immune function, and the maintenance of cellular health
Thus, topical glutathione does not work effectively and does not promise uniform results
In 2014, an abstract was published in the FASEB journal examining the effects of 30 days of 675 mg/day of Protandim on serum lipid peroxidation in 13 overweight and/or obese subjects [21]
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