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Available human studies are characterized by relatively small sample sizes, heterogeneity in dosing regimens, and short intervention durations, which restrict the ability to draw firm conclusions regarding efficacy and optimal therapeutic windows

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doi: 10.1111/j.2040-1124.2010.00022.x 125 KleinertMSachsSHabeggerKMHofmannSMMllerTDKleinertMet al