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Antiviral Res 2009;81(2):156-165

However, if the individual is not already receiving GLP-1 RA or dual GIP and GLP-1 RA therapy, an agent from these classes should be started first, as it may be sufficient for achieving individualized A1C goals but with lower risk of hypoglycemia and with favorable weight, cardiovascular, kidney, and liver profiles

313 In AD mouse models, NNT expression is reduced, 314 and the activities of key metabolic enzymes, such as aconitase, -KG dehydrogenase, and malic dehydrogenase (MDH), are inhibited, 315,316 further impairing energy metabolism and antioxidant capacity