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Bauer TM, Santoro A, Lin CC, Garrido-Laguna I, Joerger M, Greil R, Spreafico A, Yau T, Goebeler ME, Hutter-Kronke ML, Perotti A, Juif PE, Lu D, Barys L, Cremasco V, Pelletier M, Evans H, Fabre C, Doi T

Notably, preclinical data characterize this receptor activation as remarkably ligand-efficient, with biologically relevant responses observed at very low ligand concentrations across in vitro and in vivo preclinical systems