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Research has shown that GLP-1, along with other gut-brain peptides like ghrelin, leptin, and galanin, acts on the mesolimbic dopamine system of the brain and influences the activation of this system by alcohol and other addictive drugs

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Treatment begins with 0.25 mg once weekly for 4 weeks as an initiation dose (not intended for glycaemic control), then increases to 0.5 mg once weekly

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