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This article does not assert that the four components produce additive, synergistic, or otherwise interacting effects when combined in any model system

In skin specifically, GHK-Cu has been extensively studied for its ability to increase collagen and elastin production, improve skin thickness and elasticity, reduce fine lines and wrinkles, improve skin firmness, reduce photodamage, reduce hyperpigmentation, and accelerate wound healing

Fisetin attenuates doxorubicin-induced cardiomyopathy and by inhibiting ferroptosis through SIRT1/Nrf2 signaling pathway activation

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