The FDA permits compounding only when a drug is officially in shortage, and both semaglutide and tirzepatide were removed from the shortage list in late 2024 and early 2025
These include: GLP-1 receptor GIP receptor Its dual receptor activity has made Tirzepatide one of the most researched peptide compounds in recent years
Lancet (London England) 397(10278):971984 Rubino D, Abrahamsson N, Davies M, Hesse D, Greenway FL, Jensen C, Lingvay I, Mosenzon O, Rosenstock J, Rubio MA, Rudofsky G, Tadayon S, Wadden TA, Dicker D (2021) Effect of continued Weekly Subcutaneous Semaglutide vs Placebo on Weight loss maintenance in adults with overweight or obesity: the STEP 4 Randomized Clinical Trial
Heres a list of sources of B12: Supplements for Vitamin B12 For people who dont have a severe deficiency or nutrient malabsorption problem, supplements may be a good option to bring levels back to normal