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While both drugs are effective in their respective areas, combining them with supplements like a low FODMAP probiotic could potentially optimize treatment outcomes

doi: 10.3389/fsurg.2022.973883 Received 20 June 2022 Accepted 12 August 2022 Published 31 August 2022 Volume 9 - 2022 Edited by Pasquale Cianci, Azienda Sanitaria Localedella Provincia di Barletta Andri Trani (ASL BT), Italy Reviewed by Abdullah Ozgur Yeniova, Tokat Gaziosmanpaa University, Turkey Marina Minafra, Ospedale civile "Lorenzo Bonomo", Italy Updates Copyright 2022 Zhao, Chen, Xing, Yu and Liu

(26) employed 630 nm LED irradiation on the knee joints of KOA model rats, observing that this treatment significantly increased the activity of endogenous antioxidant enzymes (SOD and catalase) in OA joints, reduced levels of lipid peroxidation damage markers such as thiobarbituric acid reactive substances (TBARS), and effectively mitigated oxidative stress-induced damage to chondrocytes