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Name: tirzepatide surmount-1 weight loss percent nejm 2022 for Obesity Treatment and Diabetes Prevention Retatrutide Phase 2 NEJM Trial:
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Your doctor may also explore alternative compounds like tirzepatide (which acts on dual GLP-1 and GIP receptors) if semaglutide alone isn't meeting your goals at tolerable doses

Digestive changes, including constipation or loose stools, may begin around day 7 and can persist longer than nausea as your gut adjusts to slower food passage

It is a hormone your gut naturally releases after eating