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Patients who have experienced unexplained severe abdominal pain or confirmed acute pancreatitis should discuss GLP-1 safety with their physician before starting therapy

Semaglutide was associated with reduced alcohol consumption and blood alcohol levels during the laboratory drinking task Participants receiving semaglutide drank less (bar graph below) and achieved lower blood alcohol levels during the end of treatment alcohol self-administration paradigm

(10) patients with urinary tract/genital infections or histories of recurring urinary tract/genital infections

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