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Long-term impact on total cost of care also remains to be seen. Whats more, at $11,500-$14,000 annual wholesale acquisition price for GLP-1a weight loss treatment, the Institute for Clinical Economic Review (ICER) cost-effectiveness analysis identified that GLP-1a weight loss therapies are over-priced two-fold to their expected value in weight loss associated reduction in cardiovascular events and diabetes development avoidance over a lifetime

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It has extensive biological properties, including antioxidant, anti-inflammatory, and anti-apoptosis effects, and stimulates mitochondrial biogenesis (Li Y et al., 2016