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One notable immunogenicity finding from that same trial is worth highlighting for researchers: antibodies developed in almost 50% of patients receiving tesamorelin, although the study authors noted this was a relatively short-duration trial and did not report this antibody development as being associated with a loss of efficacy or a distinct safety signal within the study period

Additionally, in mice with APP mutations, the implementation of TRE alongside a 3040% reduction in calorie intake significantly mitigated the accumulation of A plaques (249) (Table 5)

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