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Zhang S, Gao H, Bao G

TB-500 is studied for structural repair mechanisms: organizing the cellular skeleton (actin), promoting cell movement to injury sites, and stimulating blood vessel formation (angiogenesis)

Indeed, degradation of AMPK1 by MAGEA3/6TRIM28 ubiquitin ligase sufficiently abolishes AMPK activation in human cancer cells 13

However, current evidence remains largely proof-of-concept, and translation requires careful evaluation of phototoxicity, cross-platform calibration, and protocol-dependent domain shift (culture media, incubator conditions, optics), so hyperspectral features are best positioned within standardized, prospectively validated multimodal pipelines rather than as stand-alone add-ons [444, 445]