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In the SURMOUNT-1 trial with 2,539 participants, patients taking 15 mg tirzepatide weekly (combined with diet and exercise) lost an average of 20.9% of their body weight over 72 weeks

In response to comments from interested parties, we agreed that, given the limited claims data available and a new outpatient indication for C2645, a payment rate for HCPCS code C2645 based on the geometric mean cost of $1.02 per mm 2 may not adequately reflect the cost of HCPCS code C2645

Hallstrand TS, Debley JS, Farin FM, Henderson WR

B-12 injections are generally considered safe when administered by a qualified healthcare professional