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In addition, BM-MSCs could also promote the recovery of tubule damage (223)

In vitro studies have documented that GHK-Cu treatment (1-10 M) increases proliferation of outer root sheath keratinocytes by 30-60% and dermal papilla cells by 20-40%, cell populations critical for hair shaft formation and follicle cycling regulation

Collectively, the above studies show that GGT also plays an important adaptive role in organs wherein it was not believed to be clinically relevant, such as the lung [19]

Interestingly, however, the lack of mitotic figures does not necessarily indicate a more benign course of the disease