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By suppressing AKT signal pathway, the main signal pathway activated by insulin, GLP-1 may reverse the tumor promoting effect by insulin in pancreatic cancer

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5.1.3 Carnitine-acylcarnitine translocase (CACT) deficiency Clinical presentation Patients with CACT deficiency (OMIM 212138) usually present in the neonatal period with severe hyperammonemia, liver failure, cardiomyopathy and respiratory distress, often with fatal outcome [23, 24, 102, 103]

By increasing reliance on fat as a primary fuel source, L-Carnitine helps preserve muscle glycogen a critical carbohydrate energy reserve during high-intensity training