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Reducing melanin production Glutathione inhibits the enzyme tyrosinase, which is responsible for melanin production, reducing pigmentation and giving the skin a radiant glow

From Mosharov et al

Most people start with 1.5 mg for about 30 days, bump to 4 mg, and if needed, go to 9 mg

Crocus sativus (saffron) in the treatment of female sexual dysfunction: A three-center, double-blind, randomized, and placebo-controlled clinical trial