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However, indirect factors such as dehydration from gastrointestinal side effects and rapid weight loss may theoretically increase stone risk

What this means practically: The litigation is active and growing, meaning the evidentiary record is still being developed New plaintiffs are still being added to the MDL Settlement negotiations are not yet at a public stage, but that can change quickly Individual state court cases are also proceeding in parallel in some jurisdictions Here is what the litigation timeline realistically suggests

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Overall, it demonstrated that teplizumab improved C-peptide levels compared to placebo at week 78, suggesting preservation of -cell function