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Research Summary Dihexa is a small peptide angiotensin IV derivative shown in preclinical studies primarily using rodent models to significantly enhance synaptogenesis, cognitive function, and neuroprotection by activating the HGF/c-Met pathway

The copper component also serves as a cofactor for superoxide dismutase (SOD-1 and SOD-3), providing direct antioxidant protection at the tissue level

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The Regulatory Background In late 2023, the FDA placed 19 widely used peptides on its Category 2 restricted list, effectively barring compounding pharmacies from preparing them