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Factors such as baseline gut motility, dietary habits, concurrent medications, and metabolic health may all influence how prominently these symptoms present

54 The phase 3 randomised controlled Study of Retratrutide in Participants with Obesity and Cardiovascular Disease (TRIUMPH-3) seeks to determine the percentage change from baseline in body weight in patients with BMI 35 kg/m 2 and established CVD (clinical trial number NCT05882045

Nevertheless, the team did emphasize that the short follow-up period in their study may be insufficient to fully capture the chronic trajectory of glaucoma development, particularly given the recent FDA approval of tirzepatide

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