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Allergic reactions remain rare but possible, especially in individuals with copper sensitivity, with symptoms including hives, swelling, difficulty breathing, and severe rash
Biochem Biophys Res Commun 405 , 173179, doi: 10.1016/j.bbrc.2011.01.002 (2011)
SAM is the methyl donor for DNA methyltransferases (DNMT1, DNMT3A, DNMT3B) that maintain methylation patterns at CpG sites, and for the histone methyltransferases (EZH2, SETD2, NSD2) that methylate histones to regulate chromatin state and gene expression
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